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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DVL1
All Species:
28.79
Human Site:
S142
Identified Species:
79.17
UniProt:
O14640
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14640
NP_004412.2
695
75187
S142
T
G
T
E
S
M
V
S
H
R
R
E
R
A
R
Chimpanzee
Pan troglodytes
Q5IS48
670
72833
S142
T
G
T
E
S
M
V
S
H
R
R
E
R
A
R
Rhesus Macaque
Macaca mulatta
XP_001105770
731
78423
S158
T
E
T
E
S
V
V
S
L
R
R
E
R
P
R
Dog
Lupus familis
XP_546713
700
75601
S142
T
G
T
E
S
M
V
S
H
R
R
E
R
A
R
Cat
Felis silvestris
Mouse
Mus musculus
P51141
695
75332
S142
T
G
T
E
S
M
V
S
H
R
R
E
R
A
R
Rat
Rattus norvegicus
Q9WVB9
695
75429
S142
T
G
T
E
S
M
V
S
H
R
R
E
R
A
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422756
833
90624
S262
T
E
T
D
S
V
V
S
S
Q
R
E
R
P
R
Frog
Xenopus laevis
Q6DKE2
717
78751
S139
T
E
T
D
S
V
V
S
A
R
R
E
R
P
G
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P51140
623
68898
Q121
T
N
R
K
L
Q
Q
Q
Q
Q
Q
H
Q
Q
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.1
60.5
95.2
N.A.
94.8
95.1
N.A.
N.A.
55.5
65.9
N.A.
N.A.
40.4
N.A.
N.A.
N.A.
Protein Similarity:
100
96.2
71.9
96.7
N.A.
96.6
96.9
N.A.
N.A.
67.5
78
N.A.
N.A.
55.5
N.A.
N.A.
N.A.
P-Site Identity:
100
100
73.3
100
N.A.
100
100
N.A.
N.A.
60
60
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
80
100
N.A.
100
100
N.A.
N.A.
80
73.3
N.A.
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
12
0
0
0
0
56
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
23
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
34
0
67
0
0
0
0
0
0
0
89
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
56
0
0
0
0
0
0
0
0
0
0
0
0
12
% G
% His:
0
0
0
0
0
0
0
0
56
0
0
12
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
12
0
0
0
12
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
56
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
34
0
% P
% Gln:
0
0
0
0
0
12
12
12
12
23
12
0
12
12
12
% Q
% Arg:
0
0
12
0
0
0
0
0
0
78
89
0
89
0
78
% R
% Ser:
0
0
0
0
89
0
0
89
12
0
0
0
0
0
0
% S
% Thr:
100
0
89
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
34
89
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _